(To see other currencies, click on price)
MORE ABOUT THIS BOOK
Main description:
This thesis addresses two fundamental areas in contemporary organic chemistry: synthesis of natural products and catalytic asymmetric synthesis. Firstly, a new methodology, developed by our research group, which allows the asymmetric synthesis of lactones, a structural unit ubiquitous in natural products, was utilised in the synthesis of a number of natural product analogues that showed significant biological activity. Secondly, the development of a catalytic asymmetric synthesis of a key structural motif present in a number of natural products and pharmaceuticals was accomplished. During the course of this work we discovered dual stereo control, which is significant because it allows the configuration of a new stereo centre to be controlled by a simple change of proton source.
Contents:
Introduction to the Total Synthesis of Lactone-Containing Natural Products using ZrCl4.- Asymmetric Synthesis of the -Methyl-Substituted Analogues of (+)-Tanikolide and (-)-Malyngolide.- Asymmetric Synthesis of Both Enantiomers of a d-Lactone Analogue of Muricatacin.- Introduction to the Development of a Catalytic Asymmetric Synthesis of Tertiary -Aryl Ketones.- A Stereoselective Switch: Enantiodivergent Approach to the Synthesis of Isoflavanones.- Asymmetric Synthesis of Tertiary -Aryl Ketones by Decarboxylative Asymmetric Protonation.
PRODUCT DETAILS
Publisher: Springer (Springer International Publishing AG)
Publication date: July, 2015
Pages: 224
Weight: 4616g
Availability: Available
Subcategories: Biochemistry
From the same series
![The Double [3+2] Photocycloaddition Reaction](https://d1bsyrmbdy97ez.cloudfront.net/photos/185x250/9783642270437.jpeg)
![The Double [3+2] Photocycloaddition Reaction](https://d1bsyrmbdy97ez.cloudfront.net/photos/185x250/9783642228599.jpeg)
