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Main description:
Renal Cell Carcinoma: Clinical Management provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in kidney cancer. The volume reviews new data about risk factors for the disease, profiles the new staging system for renal cell carcinoma (RCC), highlights our current understanding of familial syndromes of RCC and their molecular genetics, and provides new perspectives about imaging of renal tumors. For localized disease, a greater appreciation of nephron-sparing approaches and the importance of preservation of renal function is discussed in detail. Advances in surgical techniques are highlighted. For metastatic disease, the molecular biology of kidney cancer is reviewed in a concise and understandable manner, including the data that has fostered novel targeted approaches that have revolutionized management. The several landmark phase III targeted therapy trials published in the last few years are placed in context with respect to current management. Integration of surgery and systemic therapy through cytoreductive and consolidative approaches has yielded provocative data that promises to further advance the field, and major advances in this domain are also be discussed.
Contents:
Section I: Localized Disease
1. Etiology of RCC: Incidence, Demographics, and Environmental Factors
By Frederic D. Birkhauser, MD, Nils Kroeger, MD, and Allan J. Pantuck, MD MS FACS
2. Pathology of Renal Cell Carcinoma
By Ming Zhou, MD PhD, Huiying He
3. Familial Renal Cell Carinoma
By Simon P. Kim, MD, MPH, Bradley C. Leibovich, MD
4. Imaging of Renal Cell Carcinoma
By Andrei S. Purysko, MD, Erick M. Remer MD, Brian R. Herts, MD
5. Prognostic Factors for Localized Renal Cell Carcinoma
By Brian R. Lane, MD, PhD.
Section II: Management of Localized RCC
6. Assessment of Oncologic Risk for Clinical Stage T1 Renal Tumors and the Emerging Role of Renal Mass BiopsyBy Matthew N. Simmons MD PhD, Steven C. Campbell MD PhD
7. Radical Nephrectomy for Localized Renal Tumors: Oncological and Renal Functional Considerations
By Paul Russo, MD FACS
8. Nephron-Sparing Surgery for Renal Cancer
By Alon Z. Weizer MD, MS, Jeffery S. Montgomery MD, MHSA, Khaled S. Hafez, MD
9. Thermal Ablation
By Surena F. Matin MD FACS, Kamran Ahrar MD
10. Active Surveillance of the Small Renal Mass
By Marc C. Smaldone, MD, Daniel Canter, MD, Alexander Kutikov, MD, Robert G. Uzzo, MD FACS
Section III: Locally Advanced Disease
11. Locally Advanced Renal Cell CarcinomaBy Stephen H. Culp, MD PhD, Christopher G. Wood, MD FACS
12. Neoadjuvant Targeted Therapy and Consolidative Surgery
By Sean P. Stroup MD. Ithaar H. Derweesh, MD
Section IV: Advanced Disease
13. Biology of RCC (VEGF, mTOR, immune aspects)
By Alexandra Arreola, W. Kimryn Rathmell, MD, PhD
14. Prognostic Factors in Advanced Renal Cell Carcinoma
By Michael M. Vickers MD, Daniel Y. C. Heng MD MPH
15. Integration of Surgery in Metastatic Renal Cancer
By Tom Powles, MBBS MRCP MD, Axel Bex, MD
16. Immunotherapy for Renal Cell Carcinoma
By Diwakar Davar, MD, Moon Fenton, MD, Leonard J Appleman, MD, PhD
17. Targeted Therapy: Vascular Endothelial Growth Factor (VEGF)
By Linda Cerbone MD, Cora N. Sternberg, MD
18. mTOR in Renal cell carcinoma
By Eric Jonasch, MD, Michel Choueiri, MD
19. Palliative and Supportive Care for Renal Cancer
By Armida Parala-Metz MD, Mellar Davis MD
PRODUCT DETAILS
Publisher: Springer (Humana Press Inc.)
Publication date: September, 2012
Pages: 373
Weight: 9335g
Availability: Available
Subcategories: Oncology, Urology
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