Main description:

This
text presents the application of current nutritional knowledge by physicians
and dietitians and incorporates emerging fields of science and important
discoveries. It contains seven major sections.
Section 1: Basic Processes at the Cellular Levels, Section 2: Arginine
Metabolism and Functions, Section 3: Arginine Status in Cells Related to Organ
Damage and Disease, Section 4: Arginine Status and Use in Healthy Individuals, Section
5: Arginine and Diseases of the Gastrointestinal Tract, Section 6: Therapeutic
uses of Arginine: Diabetes, Obesity and Cardiovascular Diseases and Section 7: Therapeutic Uses of Arginine: Cancer, Wound
Healing and Infectious Disease.

Written
by authors of international and national standing, leaders in the field and
trendsetters, Arginine in Clinical Nutrition is essential reading for
nutritionists and dietitians, public health scientists, doctors,
epidemiologists, health care professionals of various disciplines, policy
makers and marketing and economic strategists.

Contents:

Section 1: Basic Processes at the
Cellular Levels

Chapter
1 - Arginine uptake by cells - Geoffrey P. Candy and Marietha J. Nel

Chapter
2 - L-arginine and the expression of HSP70 and p-53 proteins - Agnieszka
Pedrycz and Victor R. Preedy

Chapter
3 - AMP-activated protein kinase and L-arginine - Srinidi
Mohan

Chapter
4 - Amidine-based compounds affecting arginine metabolism - Cristina
Maccallini, Marialuigia Fantacuzzi and Rosa Amoroso

Chapter
5 - Oxy- and sulfoanalogues of L-arginine - Tatyana Dzimbova and Tamara
Pajpanova

Chapter
6 - Regulation of expression and activity of L-arginine transporters by
nutrients and hormones: A focus in transcriptional mechanisms regulated by
glucose and insulin - Marcelo Gonzalez

Chapter
7 - Arginine, pancreatic beta cell
function and diabetes: mechanisms of stimulated insulin release and pathways of
metabolism - Philip Newsholme, Kevin N. Keane, Mina Elahy and Vinicius Fernandes Cruzat

Chapter 8 - Erythrocytes by-products of arginine
catabolism - Martha Lucinda Contreras-Zentella and Rolando Hernandez-Munoz

Section 2: Arginine Metabolism
and Functions

Chapter
9 - Arginine synthesis from enteral proline - Christopher Tomlinson, Ronald
O. Ball and Paul B. Pencharz

Chapter
10 - Arginine and macrophages: role in classical and alternative activation

- Jorge
Lloberas, Manuel Modolell and Antonio Celada

Chapter 11 - Arginine and TNF alpha
production in macrophages: a focus on metabolism, ageing, metabolic syndrome
and type 2 diabetes
- Charlotte
Breuillard, Christophe Moinard and Marie-Chantal Farges

Chapter 12 - Arginine metabolism impairment during sepsis
and diseases: causes and consequences - Christophe
Moinard, Charlotte Breuillard and Christine Charrueau

Chapter
13 - Use of arginine with Growth Hormone Releasing Hormone (GHRH) and the
endocrine response - Giulia Brigante and Vincenzo Rochira

Chapter
14 - Serum arginase in healthy subjects and nitric oxide - Keiki Ogino and Kei
Takemoto

Section 3: Arginine Status in
Cells Related to Organ Damage and Disease

Chapter
15 - Protein Arginine Methylation of
RNA-binding Proteins and Their Impact on Human Diseases - Michael C. Yu and
Christopher A. Jackson

Chapter
16 - DNA-arginine adducts and implications in disease - Haseeb Ahsan

Chapter
17 - Homoarginine and L-arginine: Glycine amidinotransferase in stroke - Chi-un
Choe, Edzard Schwedhelm and Dorothee Atzler

Chapter
18 - The L-arginine/asymmetric dimethylarginine (ADMA) ratio in health and
disease: an overview - Murat Celik and Hilmi Umut Unal

Chapter
19 - Arginine and its transporters in colorectal cancer - Bingguan Chen, Weimin
Wang, Kang Ding, Junchen Wang, Peng Gao, Guowang Xu and Hai Hu

Chapter
20 - Arginine Uptake and Its Role in the Survival of Breast Cancer Cells -
Catherine K. L. Too and Salma A. Abdelmagid

Section 4: Arginine Status and Use
in Healthy Individuals

Chapter
21 - Arginine production during pregnancy - Farook Jahoor, Jean W. Hsu,
Pratibha Dwarkanath, Minerva M. Thame and Anura V. Kurpad

Chapter
22 - L-arginine in the uterus and placenta and during gestation in mammals -
Jonathan M. Greene and Peter L. Ryan

Chapter
23 - Oral L-arginine supplementation in young males: endocrinology, metabolic,
and physiological responses at rest and during exercise - Scott C. Forbes

Chapter
24 - Metabolic precursors of
L-Arginine supplementation in sport: a focus on L-Citrulline and L-Ornithine - Antoni
Pons, Raul Bescos, Antoni Sureda and Josep A. Tur

Section 5: Arginine and Diseases
of the Gastrointestinal Tract

Chapter
25 - Arginine and its use in ameliorating Cryptosporidium
parvum infection in undernourished children - Reinaldo Barreto Oria,
Orleancio Gomes Ripardo de Azevedo, Theides
Batista Carneiro, Aldo Angelo Lima
and Richard L. Guerrant

Chapter
26 - Arginine and Inflammatory Bowel Disease (IBD) - Wenkai
Ren, Gang Liu, Shuai Chen and Yulong Yin

Chapter
27 - Dietary L-arginine and
intestinal recovery - Igor
Sukhotnik

Chapter
28 - Enteral and parenteral arginine supplementation in intestinal ischemia and
reperfusion injury - Chun-Hong Lai and Hui-Chen Lo

Chapter
29 - Mucosal Protection by Arginine in the Upper Gastrointestinal Tract - Koji
Takeuchi

Chapter
30 - Enteral L-arginine and necrotizing enterocolitis - Sophia Zachaki,
Stavroula Gavrili, Elena Polycarpou and Vasiliki I. Hatzi

Section 6: Therapeutic uses of
Arginine: Diabetes, Obesity and Cardiovascular Diseases

Chapter 31 - L-arginine
usage in Type I diabetes: From the autoimmune event to human dietary
supplementation - Mauricio Krause, Ana Paula
Trussardi Fayh and Alvaro Reischak-Oliveira

Chapter 32
- Oral l-arginine supplementation and glucose metabolism and vascular function
- Lucilla D. Monti, Elena Galluccio, Barbara Fontana and Piermarco Piatti

Chapter
33 - Arginine enriched apples and diabetic control - Andrea
Escudero, Jorge Moreno, Jesenia Acurio and Carlos Escudero

Chapter
34 - Beneficial impact of cod protein, arginine and other
amino acids on insulin sensitivity - Veronique
Ouellet, S. John Weisnagel, Denis R. Joanisse, Charles Lavigne, Junio Dort,
Andre Marette and Helene Jacques

Chapter
35 - Obese subjects and supplemental L-arginine - Pawel Bogdanski, Joanna
Suliburska Matylda Kregielska-Narozna, Anna
Jablecka and Jaroslaw Walkowiak

Chapter
36 - Mitochondrial cardiomyopathy and usage of L-arginine - Kenichiro Arakawa,
Masamichi Ikawa, Hiroshi Tada, Hidehiko Okazawa
and Makoto Yoneda

Chapter
37 - Arginine Measurement and Concentrations in Hypertension and other
Cardiovascular Disease - Cameron Naidoo and Geoffrey P. Candy

Chapter
38 - L-Arginine and cardiovascular disease - Norbert
J. Tripolt and Harald Sourij

Chapter
39 - Arginine therapy in sickle cell disease - Claudia R. Morris

Section
7: Therapeutic Uses
of Arginine: Cancer, Wound Healing and Infectious Disease

Chapter
40 - Role of arginine in surgical patients with head and neck cancer - Daniel de Luis, Rocio Aller and Pablo Casas-Rodera

Chapter
41 - Arginine-Incorporated Albumin Mesospheres: A Drug Delivery System for
Cancer Therapy - Hung-Yen Lee, Kamal A. Mohammed and Nasreen Najmunnisa

Chapter
42 - Use of L-arginine and glycine supplementation to reduce radiotherapy
damage -Cristina Fajardo Diestel, Nara Limeira
Horst, Alessandra da Rocha Pinheiro Mulder and Ruy Garcia Marques

Chapter
43 - Arginine in Cancer Therapy - Lynn G. Feun, Medhi Wangpaichitr, Chunjing Wu,
Ying-Ying Li, Min You, Macus Tien Kuo, Niramol Savaraj

Chapter
44 - Mechanisms of Arginine-Auxotrophic Response and Their Cancer Therapeutic
Implications - Wen-Bin Tsai, Yan Long, Niramol Savaraj, Lynn G. Feun and Macus
Tien Kuo

Chapter
45 - The role of arginine in wound healing - Alan N. Gould and Geoffrey P.
Candy

Chapter
46 - L-arginine and bacterial translocation: implications for health - Mirelle
Lomar Viana, Simone de Vasconcelos Generoso, Rosana das Gracas Carvalho dos
Santos, Valbert Nascimento Cardoso and Maria Isabel Toulson Davisson Correia

Chapter
47 - L-arginine in Pulmonary Tuberculosis - Anna P. Ralph

Chapter
48 - Arginine in Health and Disease: Recommended Resources
and Further Reading - Rajkumar Rajendram, Vinood B.
Patel and Victor R. Preedy