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MORE ABOUT THIS BOOK
Main description:
The goal of this volume is to offer a highly readable and comprehensive overview on our present knowledge of the positive and negative effects of UV-exposure. The book focuses on vitamin D and skin cancer. Topics that are discussed in-depth by leading researchers and clinicians range from the newest findings in endocrinology, epidemiology, histology, photobiology, immunology, cytogenetics and molecular pathology to new concepts for prophylaxis and treatment.
Contents:
CONTENTS 1. Sunlight, UV-Radiation, Vitamin D and Skin Cancer: How Much Sunlight Do We Need?....................................................... 1 Michael F. Holick Abstract................................................................................................................................. 1 Prehistorical and Historic Perspectives.............................................................................. 1 Photoproduction of Vitamin D3............................................................................................ 2 Factors Controlling Cutaneous Vitamin D Synthesis........................................................ 2 Sources and Metabolism of Vitamin D................................................................................ 4 Role of Vitamin D in the Prevention of Chronic Diseases................................................. 5 Vitamin D Deficiency Pandemic.......................................................................................... 7 Sunlight, Vitamin D and the Skin Cancer Conundrum.................................................... 7 Conclusion.......................................................................................................................... 10 2. Solar Ultrav iolet Irradiance and Cancer Incidence and Mortality...................................................................... 16 William B. Grant Introduction........................................................................................................................ 16 Cancer................................................................................................................................. 16 Other Diseases for Which Solar UVB and Vitamin D Are Beneficial/Protective.......... 25 Summary and Conclusion.................................................................................................. 25 3. Vitamin D Status and Cancer Incidence and Mortality............................................................................................. 31 Edward Giovannucci Introduction........................................................................................................................ 31 Ecologic Studies of Sun Exposure..................................................................................... 32 Case-Control and Cohort Studies of Sun Exposure........................................................ 32 Prospective Studies of Circulating 25(OH)vitamin D and Cancer Risk........................ 33 Studies of Vitamin D Intake............................................................................................... 35 Randomized Trial of Vitamin D Intake and Colorectal Cancer..................................... 36 Solar Radiation, Vitamin D and Survival Rate of Colon Cancer................................... 36 Vitamin D and Cancer Rates in United States Black Men.............................................. 37 Synthesis of Evidence Regarding Sun Exposure, Vitamin D and Cancer Incidence and Mortality........................................................................ 38 Implications for Future Research...................................................................................... 39 4. Sun Exposure and Cancer Surviva l in Norway: Changes in the Risk of Death with Season of Diagnosis and Latitude.................................................................... 43 Alina Carmen Porojnicu, Arne Dahlback and Johan Moan Abstract............................................................................................................................... 43 Introduction.............................................
PRODUCT DETAILS
Publisher: Springer (Springer-Verlag New York Inc.)
Publication date: November, 2010
Pages: 344
Weight: 662g
Availability: Available
Subcategories: Dermatology, Oncology
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