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The Pathologic Physiology of Dementia
With Indications for Diagnosis and Treatment
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Contents:

1. Historical Overview of Dementia.- Prelude to the Modern Era.- Age of Alzheimer and Kraepelin.- History of Alzheimer's Disease.- References.- 2. Clinical Manifestations as a Determinant of Dementia.- General Considerations.- Functional Mental Syndromes as a Manifestation of Brain Disease.- Acute Confusion.- Specialized Syndromes in Dementia.- Creutzfeldt-Jakob Disease.- Kluver-Bucy Syndrome (Limbic Encephalitis).- Normal Pressure Hydrocephalus.- Summary of Specialized Syndromes.- Summary of Clinical Manifestations.- References.- 3. Diagnostic Tests of Dementia as Research Tools.- Psychological Tests of Intelligence.- Electroencephalography.- Radiographic Technique.- Morphologic and Chemical Assay of Brain Tissue.- References.- 4. Treatment of Senile Dementia.- Acute Confusion.- Circulatory Agents.- Metabolic Stimulants.- Psychoactive Drug Therapy.- Antiviral Therapy.- Surgical Management.- Shunt Therapy.- Carotid Surgery.- Conclusions.- References.- 5. Epidemiology of Dementia.- General Considerations.- Previous Surveys of Senile Dementia.- Cross-Sectional Survey.- Larsson Survey.- Autopsy Studies.- The GM Survey.- Characteristics of the Population.- Methods.- Diagnosis of Dementia.- Results.- Etiologic Implications of Epidemiology.- Aging.- Heredity.- Slow Virus Infection.- Concluding Remarks.- References.- 6. Current Evaluation of Pathologic Correlates of Dementia.- Congophilic Angiopathy.- Senile Plaques.- Endogenous Plaque Formation.- Exogenous Origin From Circulating Immunoproteins.- Neurofibrillary Tangles.- Creutzfeldt-Jakob Disease.- Other Pathologic Correlates.- Aluminum.- Lipofuscin.- Granulovacuolar Degeneration.- Pathogenetic Implications of Pathology.- References.- 7. Arteriosclerotic Dementia.- Dementia Following Multiple Strokes.- Little Strokes.- Diffuse Cerebral Ischemia.- Ischemia Due to Macrovascular Disease.- Carotid Artery Occlusion.- Vertebrobasilar Insufficiency.- Ischemia Due to Microvascular Disease.- Cerebral Blood Flow Study of Dementia.- Summary.- References.- 8. Critical Evaluation of the Concept of Mental Aging.- Functional Aspects of the Elderly Brain.- Mental Behavior in the Aged.- Memory.- Cognitive Function.- Psychoses After 65.- Electroencephalography.- Routine EEG.- Visual Evoked Response (VER).- Cerebral Blood Flow.- Immunologic Indices of Aging.- Pathology of the Aged Brain.- Brain Weight as a Determinant of Atrophy.- Neuron Loss With Aging.- Senile Plaques, Neurofibrillary Tangles, Granulovacuolar Degeneration.- Lipofuscin.- Abnormalities of the Peripheral Neuron.- Epidemiology of Mental Aging.- Cross-Sectional Survey of Effectiveness.- Longitudinal Survey of Aging.- Summary of Longitudinal Surveys.- Psychological Test of Intelligence.- Psychometrics as Determinants of Longevity.- Biologic Factors of Longevity.- Conclusions.- Summary of Mental Aging.- References.- 9. Nature and Cause of Alzheimer's Disease: The Case for Slow Virus Infection.- Nature of AD.- Clinical Indicators.- Diagnostic Criteria.- Epidemiology.- Pathologic Data.- Etiologic Potential for AD.- Metabolic Disease.- Autoimmune Disease.- Metallic Intoxication.- Slow Virus Infection.- Concept of Slow Virus Infection.- Comparison of AD and Slow Virus Infection.- References.


PRODUCT DETAILS

ISBN-13: 9783642884399
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Publication date: April, 2012
Pages: 158
Weight: 302g
Availability: Available
Subcategories: General Practice
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