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MORE ABOUT THIS BOOK
Main description:
This volume presents a compendium of the most recent and advanced methods applied to the rapidly expanding field of telomerase inhibition. The techniques described provide the researcher with a diverse and comprehensive set of tools for the study of telomerase inhibition. The volume is aimed at biochemists, molecular biologists, cancer researchers, and geneticists.
Contents:
Contents:
Preface
Contributors
1. Methods of Telomerase Inhibition
Lucy G. Andrews and Trygve O. Tollefsbol
2. Telomerase Inhibition by Synthetic Nucleic Acids and
Chemosensitization in Human Bladder Cancer Cell Lines
Kai Kraemer, Susanne Fuessel, and Axel Meye
3. hTERT Knockdown in Human Embryonic Kidney Cells Using
Double-Stranded RNA
Serene R. Lai, Lucy G. Andrews, and Trygve O. Tollefsbol
4. RNA Interference Using a Plasmid Construct Expressing Short Hairpin
RNA
Serene R. Lai, Lucy G. Andrews, and Trygve O. Tollefsbol
5. Retrovirus-mediated RNA Interference: Targeting hTERT Through Stable
Expression of Short Hairpin RNA
Amanda P. Cunningham, Lucy G. Andrews, and Trygve O. Tollefsbol
6. Telomerase Inhibition and Telomere Targeting in Hematopoietic Cell
Lines with Small Non-Nucleosidic Synthetic Compounds (BIBR1532)
Hesham El Daly and Uwe M. Martens
7. Uses of Telomerase Peptides in Anti-tumor Immune Therapy
He Li, Indzi Katik, and Jun-Ping Liu
8. Establishing Cell-based Reporter Systems for the Analysis of hTERT
expression
Yi-Yuan Huang, Jing-Wen Shih, and Jing-Jer Lin
9. Telomerase RNA Inhibition Using Antisense Oligonucleotide Against
Human Telomerase RNA Linked to a 2', 5'-Oligoadenylate (2-5A)
Yasuko Kondo and Seji Kondo
10. Knockdown of Telomerase RNA Using Hammerhead Ribozymes and RNA
Interference
Shang Li, Mehdi Nosrati, and Mohammed Kashani-Sabet
11. Evaluation of Tankyrase Inhibition in Whole Cells
Tomohazu Ohishi, Takashi Tsuruo, and Hiroyuki Seimiya
12. Inhibition of Telomerase by Targeting MAP Kinase Signaling
Dakang Xu, He Li, and Jun-Ping Li
13. Screening of Telomerase Inhibitors
Elke Kleideiter, Kamilla Piotrowska, and Ulrich Klotz
14. Telomerase Inhibition Combined with Other Chemotherapeutic Reagents
to Enhance Anti-Cancer Effect
Tetsuzo Tauchi, Junko H. Ohyashiki,and Kazuma Ohyashiki
PRODUCT DETAILS
Publisher: Springer (Humana Press Inc.)
Publication date: December, 2011
Pages: 203
Weight: 306g
Availability: Available
Subcategories: Biochemistry, Genetics, Oncology
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